KMID : 0390020100200020122
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Pediatric Allergy and Respiratory Disease 2010 Volume.20 No. 2 p.122 ~ p.129
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Clinical Characteristics of Chlamydia trachomatis Respiratory Tract Infection in Young Infants
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Hwang Seon-Tae
Eun Byung-Wook Sun Yong-Han Kim Jee-Eun Sim So-Yeon Cho Kang-Ho Ryoo Eell Choi Deok-Young Son Dong-Woo Tchah Hann Jeon In-Cheol
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Abstract
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Background:Chlamydia trachomatis (C. trachomatis) is the most prevalent etiology of sexually transmitted diseases and also a cause of respiratory infections in infants. The purposes of this study were to determine the epidemiology, presentation, and laboratory findings of C. trachomatis respiratory infection, and to investigate its severity and hospital courses.
Methods:Between February 2002 and January 2010, we enrolled infants younger than 6 months admitted to Gil Hospital with a diagnosis of acute bronchiolits and pneumonia. Clinical findings and demographic data were reviewed in all patients. Basic laboratory examinations included white blood cell and eosinophil count. C. trachomatis was detected by enzyme immunoassay for C. trachomatis specific immunoglobulin M.
Results:Of 1,708 patients, C. trachomatis was detected in 142 (8.3%). The incidence increased from 2002 to 2009 and was higher in spring. C. trachomatis infection was distinguished by less fever (P<0.01) and more crackle (P<0.05) on auscultation, and strongly correlated with eosinophilia (P=0.01). The severity and clinical course of C. trachomatis infection was similar to those of infections by the other etiologies.
Conclusions:C. trachomatis is prevalent among infants younger than 6 months with a diagnosis of acute bronchiolits and pneumonia. We must consider C. trachomatis as the etiologic agent in infantile respiratory infections and must make more effort to detect C. trachomatis.
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KEYWORD
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Chlamydia trachomatis, Infant, Respiratory infections, Diagnosis
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